Deprecated: Return type of WP_Theme::offsetExists($offset) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-theme.php on line 554
Deprecated: Return type of WP_Theme::offsetGet($offset) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-theme.php on line 595
Deprecated: Return type of WP_Theme::offsetSet($offset, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-theme.php on line 535
Deprecated: Return type of WP_Theme::offsetUnset($offset) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-theme.php on line 544
Deprecated: Return type of WP_REST_Request::offsetExists($offset) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/rest-api/class-wp-rest-request.php on line 960
Deprecated: Return type of WP_REST_Request::offsetGet($offset) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/rest-api/class-wp-rest-request.php on line 980
Deprecated: Return type of WP_REST_Request::offsetSet($offset, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/rest-api/class-wp-rest-request.php on line 992
Deprecated: Return type of WP_REST_Request::offsetUnset($offset) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/rest-api/class-wp-rest-request.php on line 1003
Deprecated: Return type of WP_Block_List::current() should either be compatible with Iterator::current(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-block-list.php on line 151
Deprecated: Return type of WP_Block_List::next() should either be compatible with Iterator::next(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-block-list.php on line 175
Deprecated: Return type of WP_Block_List::key() should either be compatible with Iterator::key(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-block-list.php on line 164
Deprecated: Return type of WP_Block_List::valid() should either be compatible with Iterator::valid(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-block-list.php on line 186
Deprecated: Return type of WP_Block_List::rewind() should either be compatible with Iterator::rewind(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-block-list.php on line 138
Deprecated: Return type of WP_Block_List::offsetExists($index) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-block-list.php on line 75
Deprecated: Return type of WP_Block_List::offsetGet($index) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-block-list.php on line 89
Deprecated: Return type of WP_Block_List::offsetSet($index, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-block-list.php on line 110
Deprecated: Return type of WP_Block_List::offsetUnset($index) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-block-list.php on line 127
Deprecated: Return type of WP_Block_List::count() should either be compatible with Countable::count(): int, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/class-wp-block-list.php on line 199
Warning: Private methods cannot be final as they are never overridden by other classes in /www/thebottomlineh_300/public/wp-content/plugins/post-state-tags/post-state-tags.php on line 77
Deprecated: load_plugin_textdomain was called with an argument that is deprecated since version 2.7.0 with no alternative available. in /www/thebottomlineh_300/public/wp-includes/functions.php on line 5507
Deprecated: Optional parameter $setting declared before required parameter $value is implicitly treated as a required parameter in /www/thebottomlineh_300/public/wp-content/plugins/simple-post-template/vendor/objectivco/wordpress-simple-settings/src/wordpress-simple-settings.php on line 46
Deprecated: Optional parameter $setting declared before required parameter $value is implicitly treated as a required parameter in /www/thebottomlineh_300/public/wp-content/plugins/simple-post-template/vendor/objectivco/wordpress-simple-settings/src/wordpress-simple-settings.php on line 64
Deprecated: Return type of tad_DI52_Container::offsetExists($offset) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/tribe-common/vendor/lucatume/di52/src/tad/DI52/Container.php on line 549
Deprecated: Return type of tad_DI52_Container::offsetGet($offset) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/tribe-common/vendor/lucatume/di52/src/tad/DI52/Container.php on line 218
Deprecated: Return type of tad_DI52_Container::offsetSet($offset, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/tribe-common/vendor/lucatume/di52/src/tad/DI52/Container.php on line 163
Deprecated: Return type of tad_DI52_Container::offsetUnset($offset) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/tribe-common/vendor/lucatume/di52/src/tad/DI52/Container.php on line 603
Deprecated: Return type of MC4WP_Container::offsetExists($offset) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/mailchimp-for-wp/includes/class-container.php on line 71
Deprecated: Return type of MC4WP_Container::offsetGet($offset) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/mailchimp-for-wp/includes/class-container.php on line 86
Deprecated: Return type of MC4WP_Container::offsetSet($offset, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/mailchimp-for-wp/includes/class-container.php on line 104
Deprecated: Return type of MC4WP_Container::offsetUnset($offset) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/mailchimp-for-wp/includes/class-container.php on line 119
Deprecated: Optional parameter $post_id declared before required parameter $meta_key is implicitly treated as a required parameter in /www/thebottomlineh_300/public/wp-content/plugins/tlp-team/lib/classes/TLPTeamHelper.php on line 436
Deprecated: Optional parameter $items declared before required parameter $fields is implicitly treated as a required parameter in /www/thebottomlineh_300/public/wp-content/plugins/tlp-team/lib/classes/TLPTeamHelper.php on line 620
Deprecated: Optional parameter $empty declared before required parameter $term_id is implicitly treated as a required parameter in /www/thebottomlineh_300/public/wp-content/plugins/tlp-team/lib/classes/TLPTeamItemSorting.php on line 67
Deprecated: Return type of Pods\Whatsit::offsetExists($offset) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/src/Pods/Whatsit.php on line 351
Deprecated: Return type of & Pods\Whatsit::offsetGet($offset) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/src/Pods/Whatsit.php on line 362
Deprecated: Return type of Pods\Whatsit::offsetSet($offset, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/src/Pods/Whatsit.php on line 375
Deprecated: Return type of Pods\Whatsit::offsetUnset($offset) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/src/Pods/Whatsit.php on line 389
Deprecated: Return type of Pods\Whatsit::jsonSerialize() should either be compatible with JsonSerializable::jsonSerialize(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/src/Pods/Whatsit.php on line 285
Deprecated: Return type of Pods\Whatsit::current() should either be compatible with Iterator::current(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/src/Pods/Whatsit.php on line 306
Deprecated: Return type of Pods\Whatsit::next() should either be compatible with Iterator::next(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/src/Pods/Whatsit.php on line 322
Deprecated: Return type of Pods\Whatsit::key() should either be compatible with Iterator::key(): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/src/Pods/Whatsit.php on line 315
Deprecated: Return type of Pods\Whatsit::valid() should either be compatible with Iterator::valid(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/src/Pods/Whatsit.php on line 329
Deprecated: Return type of Pods\Whatsit::rewind() should either be compatible with Iterator::rewind(): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-content/plugins/pods/src/Pods/Whatsit.php on line 299
Deprecated: DateTime::__construct(): Passing null to parameter #1 ($datetime) of type string is deprecated in /www/thebottomlineh_300/public/wp-includes/script-loader.php on line 333
Deprecated: strtolower(): Passing null to parameter #1 ($string) of type string is deprecated in /www/thebottomlineh_300/public/wp-includes/formatting.php on line 2145
Notice: register_post_type was called incorrectly. Post type names must be between 1 and 20 characters in length. Please see Debugging in WordPress for more information. (This message was added in version 4.2.0.) in /www/thebottomlineh_300/public/wp-includes/functions.php on line 5665
Deprecated: Return type of Requests_Cookie_Jar::offsetExists($key) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/Requests/Cookie/Jar.php on line 63
Deprecated: Return type of Requests_Cookie_Jar::offsetGet($key) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/Requests/Cookie/Jar.php on line 73
Deprecated: Return type of Requests_Cookie_Jar::offsetSet($key, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/Requests/Cookie/Jar.php on line 89
Deprecated: Return type of Requests_Cookie_Jar::offsetUnset($key) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/Requests/Cookie/Jar.php on line 102
Deprecated: Return type of Requests_Cookie_Jar::getIterator() should either be compatible with IteratorAggregate::getIterator(): Traversable, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/Requests/Cookie/Jar.php on line 111
Deprecated: Return type of Requests_Utility_CaseInsensitiveDictionary::offsetExists($key) should either be compatible with ArrayAccess::offsetExists(mixed $offset): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/Requests/Utility/CaseInsensitiveDictionary.php on line 40
Deprecated: Return type of Requests_Utility_CaseInsensitiveDictionary::offsetGet($key) should either be compatible with ArrayAccess::offsetGet(mixed $offset): mixed, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/Requests/Utility/CaseInsensitiveDictionary.php on line 51
Deprecated: Return type of Requests_Utility_CaseInsensitiveDictionary::offsetSet($key, $value) should either be compatible with ArrayAccess::offsetSet(mixed $offset, mixed $value): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/Requests/Utility/CaseInsensitiveDictionary.php on line 68
Deprecated: Return type of Requests_Utility_CaseInsensitiveDictionary::offsetUnset($key) should either be compatible with ArrayAccess::offsetUnset(mixed $offset): void, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/Requests/Utility/CaseInsensitiveDictionary.php on line 82
Deprecated: Return type of Requests_Utility_CaseInsensitiveDictionary::getIterator() should either be compatible with IteratorAggregate::getIterator(): Traversable, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice in /www/thebottomlineh_300/public/wp-includes/Requests/Utility/CaseInsensitiveDictionary.php on line 91
Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/thebottomlineh_300/public/wp-includes/class-wp.php on line 173
Deprecated: ltrim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/thebottomlineh_300/public/wp-includes/wp-db.php on line 3030
Warning: Cannot modify header information - headers already sent by (output started at /www/thebottomlineh_300/public/wp-includes/class-wp-block-list.php:14) in /www/thebottomlineh_300/public/wp-includes/feed-rss2.php on line 8 The Bottom Line
https://staging-thebottomlineh.kinsta.cloud
A compendium of critical appraisals in Intensive Care Medicine research and related specialtiesTue, 04 Jan 2022 14:10:36 +0000en-GB
hourly
1 https://wordpress.org/?v=5.8.14https://staging-thebottomlineh.kinsta.cloud/wp-content/uploads/2016/05/cropped-tbl-favicon-2-32x32.pngThe Bottom Line
https://staging-thebottomlineh.kinsta.cloud
3232Critical Care Evidence Updates – December 2021
https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-december-2021/?utm_source=rss&utm_medium=rss&utm_campaign=critical-care-evidence-updates-december-2021
https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-december-2021/#respondTue, 04 Jan 2022 14:10:36 +0000https://staging-thebottomlineh.kinsta.cloud/?p=10239What’s new in the Critical Care literature – monthly updates]]>https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-december-2021/feed/0PALACS
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/palacs/?utm_source=rss&utm_medium=rss&utm_campaign=palacs
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/palacs/#respondFri, 31 Dec 2021 01:04:56 +0000https://staging-thebottomlineh.kinsta.cloud/?p=10192 Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery Mario Gaudino, The Lancet Dec 4 2021; 398: 2075–83 https://doi.org/10.1016/S0140-6736(21)02490-9 Clinical Question In selected patients undergoing cardiac surgery, does posterior left pericardiotomy compared with usual care, reduce the incidence of postoperative atrial fibrillation? Background Atrial fibrillation is common following cardiac surgery with approximately one-third of patients developing […]]]>https://staging-thebottomlineh.kinsta.cloud/summaries/icm/palacs/feed/0CONTROLING
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/controling/?utm_source=rss&utm_medium=rss&utm_campaign=controling
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/controling/#respondFri, 17 Dec 2021 11:54:47 +0000https://staging-thebottomlineh.kinsta.cloud/?p=10194Individualised versus conventional glucose control in critically-ill patients: the CONTROLING study—a randomized clinical trial Bohé. Intensive Care Medicine 2021. https://doi.org/10.1007/s00134-021-06526-8 Clinical Question In critically unwell adults does targeting individualised glycaemic control compared to glycaemia < 180 mg/dL improve 90 day mortality? Background Hyperglycaemia has been shown to result in worse outcomes in the critically ill, especially in non-diabetic patients In […]]]>https://staging-thebottomlineh.kinsta.cloud/summaries/icm/controling/feed/0Critical Care Evidence Updates – November 2021
https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-november-2021/?utm_source=rss&utm_medium=rss&utm_campaign=critical-care-evidence-updates-november-2021
https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-november-2021/#respondThu, 16 Dec 2021 10:54:55 +0000https://staging-thebottomlineh.kinsta.cloud/?p=10215What’s new in the Critical Care literature – monthly updates]]>https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-november-2021/feed/0COMBAT-COVID
https://staging-thebottomlineh.kinsta.cloud/summaries/combat-covid/?utm_source=rss&utm_medium=rss&utm_campaign=combat-covid
https://staging-thebottomlineh.kinsta.cloud/summaries/combat-covid/#respondFri, 10 Dec 2021 10:36:49 +0000https://staging-thebottomlineh.kinsta.cloud/?p=10166In mechanically ventilated patients with COVID-19 and severe endotheliopathy, does prostacylin compared with placebo, improve days alive without ventilation by day 28?]]>https://staging-thebottomlineh.kinsta.cloud/summaries/combat-covid/feed/0COCA
https://staging-thebottomlineh.kinsta.cloud/summaries/coca/?utm_source=rss&utm_medium=rss&utm_campaign=coca
https://staging-thebottomlineh.kinsta.cloud/summaries/coca/#respondFri, 03 Dec 2021 16:20:28 +0000https://staging-thebottomlineh.kinsta.cloud/?p=10160In patients with out-of-hospital cardiac arrest, does calcium compared with placebo, improve sustained return of spontaneous circulation?]]>https://staging-thebottomlineh.kinsta.cloud/summaries/coca/feed/0Critical Care Evidence Updates – October 2021
https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-october-2021/?utm_source=rss&utm_medium=rss&utm_campaign=critical-care-evidence-updates-october-2021
https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-october-2021/#respondThu, 18 Nov 2021 13:31:28 +0000https://staging-thebottomlineh.kinsta.cloud/?p=10157What’s new in the Critical Care literature – monthly updates
]]>https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-october-2021/feed/0SILENCE
https://staging-thebottomlineh.kinsta.cloud/summaries/silence/?utm_source=rss&utm_medium=rss&utm_campaign=silence
https://staging-thebottomlineh.kinsta.cloud/summaries/silence/#respondWed, 17 Nov 2021 10:45:28 +0000https://staging-thebottomlineh.kinsta.cloud/?p=9874In patients near end of life, does subcutaneous scopolamine butylbromide compared with placebo, reduce the incidence of death rattle?]]>https://staging-thebottomlineh.kinsta.cloud/summaries/silence/feed/0SNOCAT
https://staging-thebottomlineh.kinsta.cloud/summaries/snocat/?utm_source=rss&utm_medium=rss&utm_campaign=snocat
https://staging-thebottomlineh.kinsta.cloud/summaries/snocat/#respondFri, 22 Oct 2021 13:31:38 +0000https://staging-thebottomlineh.kinsta.cloud/?p=9594Effect of Out-of-Hospital Sodium Nitrite on Survival to Hospital Admission After Cardiac Arrest: A Randomized Clinical Trial Kim @uwcardiology. JAMA. 2021 January 12;325(2):138-145. doi: 10.1001/jama.2020.24326. Clinical Question In patients with out-of-hospital cardiac arrest, does sodium nitrite, compared with placebo, improve survival to hospital admission? Background Out-of-hospital cardiac arrest continues to have a high risk of morbidity and mortality Nitrate therapy […]]]>https://staging-thebottomlineh.kinsta.cloud/summaries/snocat/feed/0VAM-IHCA
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/vam-ihca/?utm_source=rss&utm_medium=rss&utm_campaign=vam-ihca
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/vam-ihca/#commentsFri, 15 Oct 2021 18:19:29 +0000https://staging-thebottomlineh.kinsta.cloud/?p=10090Effect of Vasopressin and Methylprednisolone vs Placebo on Return of Spontaneous Circulation in Patients With In-Hospital Cardiac Arrest: A Randomized Clinical Trial Anderson et al. JAMA 2021. doi:10.1001/jama.2021.16628 Clinical Question In adult patients suffering an in-hospital cardiac arrest (IHCA) does the use of vasopressin and methylprednisolone compared to a placebo result in increased rates of return of spontaneous circulation (ROSC)? […]]]>https://staging-thebottomlineh.kinsta.cloud/summaries/icm/vam-ihca/feed/1COAST
https://staging-thebottomlineh.kinsta.cloud/summaries/coast/?utm_source=rss&utm_medium=rss&utm_campaign=coast
https://staging-thebottomlineh.kinsta.cloud/summaries/coast/#respondFri, 08 Oct 2021 15:16:10 +0000https://staging-thebottomlineh.kinsta.cloud/?p=9869In hypoxic African children (oxygen saturations of between 80 and 91%) with pneumonia, does oxygen therapy reduce mortality when compared with a permissive hypoxia (no oxygen) strategy?
In severely hypoxic children (oxygen saturations less than 80%), does high-flow nasal therapy reduce mortality when compared with low-flow oxygen therapy?]]>https://staging-thebottomlineh.kinsta.cloud/summaries/coast/feed/0Critical Care Evidence Updates – September 2021
https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-september-2021/?utm_source=rss&utm_medium=rss&utm_campaign=critical-care-evidence-updates-september-2021
https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-september-2021/#respondWed, 06 Oct 2021 08:51:12 +0000https://staging-thebottomlineh.kinsta.cloud/?p=10080What’s new in the Critical Care literature – monthly updates]]>https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-september-2021/feed/0COVERT MI
https://staging-thebottomlineh.kinsta.cloud/summaries/covert-mi/?utm_source=rss&utm_medium=rss&utm_campaign=covert-mi
https://staging-thebottomlineh.kinsta.cloud/summaries/covert-mi/#respondMon, 04 Oct 2021 19:56:41 +0000https://staging-thebottomlineh.kinsta.cloud/?p=9944In patients who present with an acute STEMI and are referred for percutaneous coronary intervention (PCI), does colchicine in comparsion with placebo reduce myocardial injury?]]>https://staging-thebottomlineh.kinsta.cloud/summaries/covert-mi/feed/0RECOVERY REGEN-COV
https://staging-thebottomlineh.kinsta.cloud/summaries/recovery-regen-cov/?utm_source=rss&utm_medium=rss&utm_campaign=recovery-regen-cov
https://staging-thebottomlineh.kinsta.cloud/summaries/recovery-regen-cov/#respondThu, 30 Sep 2021 21:29:01 +0000https://staging-thebottomlineh.kinsta.cloud/?p=9857Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial @PeterHorby. medRxiv pre-print 2021 doi: https://doi.org/10.1101/2021.06.15.21258542 Clinical Question In hospitalised patients with COVID-19, does the addition of monoclonal antibodies REGEN-COV (carsirivimab & imdevimab) to standard care, compared with standard care alone, improve 28 day mortality? Background Monoclonal antibodies have been shown to be […]]]>https://staging-thebottomlineh.kinsta.cloud/summaries/recovery-regen-cov/feed/0The REST Trial
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/the-rest-trial/?utm_source=rss&utm_medium=rss&utm_campaign=the-rest-trial
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/the-rest-trial/#commentsMon, 13 Sep 2021 07:08:00 +0000https://staging-thebottomlineh.kinsta.cloud/?p=9920In mechanically ventilated patients with acute hypoxaemic respiratory failure, does lowering tidal volume using extracorporeal carbon dioxide removal, compared with conventional low tidal volume ventilation, improve day 90 all-cause mortality?]]>https://staging-thebottomlineh.kinsta.cloud/summaries/icm/the-rest-trial/feed/1COVID STEROID 2
https://staging-thebottomlineh.kinsta.cloud/summaries/covid-steroid-2/?utm_source=rss&utm_medium=rss&utm_campaign=covid-steroid-2
https://staging-thebottomlineh.kinsta.cloud/summaries/covid-steroid-2/#respondThu, 09 Sep 2021 09:38:49 +0000https://staging-thebottomlineh.kinsta.cloud/?p=9836In patients with severe COVID, does 12mg dexamethasone vs 6mg dexamethasone increase the number of days alive without life support at 28 days?]]>https://staging-thebottomlineh.kinsta.cloud/summaries/covid-steroid-2/feed/0COV-BARRIER
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/cov-barrier/?utm_source=rss&utm_medium=rss&utm_campaign=cov-barrier
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/cov-barrier/#respondThu, 09 Sep 2021 09:31:21 +0000https://staging-thebottomlineh.kinsta.cloud/?p=9932In hospitalised adult patient with COVID-19, does baricitinib compared with placebo decrease a composite outcome of progression of illness and mortality?]]>https://staging-thebottomlineh.kinsta.cloud/summaries/icm/cov-barrier/feed/0TOMAHAWK
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/tomahawk/?utm_source=rss&utm_medium=rss&utm_campaign=tomahawk
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/tomahawk/#respondSun, 05 Sep 2021 06:31:48 +0000https://staging-thebottomlineh.kinsta.cloud/?p=9882Angiography after Out-of-Hospital Cardiac Arrest without ST-Segment Elevation Desch S et al. NEJM 2021. DOI: 10.1056/NEJMoa2101909 Clinical Question In adults > 30 years old suffering out-of-hospital cardiac arrest (OOHCA) without ST elevation on their ECG does routine immediate coronary angiography compared to a delayed or selective approach to coronary angiography improve 30-day all-cause mortality? Background The DISCO pilot study showed […]]]>https://staging-thebottomlineh.kinsta.cloud/summaries/icm/tomahawk/feed/0Critical Care Evidence Updates – August 2021
https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-august-2021/?utm_source=rss&utm_medium=rss&utm_campaign=critical-care-evidence-updates-august-2021
https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-august-2021/#respondSat, 04 Sep 2021 16:29:00 +0000https://staging-thebottomlineh.kinsta.cloud/?p=9923What's new in the Critical Care literature - monthly updates ]]>https://staging-thebottomlineh.kinsta.cloud/blog/critical-care-evidence-updates-august-2021/feed/0DOREMI
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/doremi/?utm_source=rss&utm_medium=rss&utm_campaign=doremi
https://staging-thebottomlineh.kinsta.cloud/summaries/icm/doremi/#respondThu, 02 Sep 2021 08:36:25 +0000https://staging-thebottomlineh.kinsta.cloud/?p=9806Milrinone as compared with Dobutamine in the Treatment of Cardiogenic Shock Matthew. N Engl J Med 2021; 385:516-525, doi: 10.1056/NEJMoa2026845 Clinical Question In patients with cardiogenic shock, does milrinone as compared with dobutamine improve the composite outcome of in-hospital death, resuscitated cardiac arrest, receipt of cardiac transplant or mechanical circulatory support, non-fatal myocardial infarction, cerebrovascular event or renal replacement therapy? […]]]>https://staging-thebottomlineh.kinsta.cloud/summaries/icm/doremi/feed/0